The Jenna-Lissa Relationship, commonly known as Jissa is the friendship pairing of Jenna Hamilton and Lissa Miller.

At first Lissa was jealous of the raw attraction between her boyfriend and Jenna. In Fateful, Lissa tells her the damage has been done and that she looks really pretty. They go to church camp together in Are You There God? It's Me, Jenna. In Surprise!, she attends Jenna's surprise party and records her surprise.

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